Journal Articles 1982 - 1991

    1982

  • Eisenhofer G. and R.H. Johnson. Effect of ethanol ingestion on plasma vasopressin and water balance in humans. American Journal of Physiology  242: R522-R527, 1982.
  • Eisenhofer G., E.A. Whiteside, D.G. Lambie and R.H. Johnson. Brain water during alcohol withdrawal. Lancet 1: 50, 1982.
  • Eisenhofer G., D.G. Lambie, R.H. Johnson, E.T.H. Tan and E.A. Whiteside. Deficient catecholamine release as the basis of orthostatic hypotension in pernicious anaemia. Jounal of Neurology, Neurosurgery and Psychiatry 45: 1053-1055, 1982.
     

    1983

  • Eisenhofer G. and R.H. Johnson. Effects of ethanol ingestion on thirst and fluid consumption in humans. American Journal of Physiology 244: R568-R572, 1983.
  • Eisenhofer G., D.G. Lambie, and R.H. Johnson. Effects of ethanol on plasma catecholamines and norepinephrine clearance. Clinical Pharmacology and Therapeutics 34: 143-147, 1983.
     

    1984

  • Eisenhofer G., R.H. Johnson, D.G. Lambie and E.A. Whiteside. Growth hormone, vasopressin, cortisol and catecholamine responses to insulin hypoglycemia in alcoholics. Alcoholism 8: 33-36, 1984.
  • Eisenhofer G., D.G. Lambie and R.H. Johnson. Effects of ethanol ingestion on alpha-adrenoceptor-mediated circulatory responses in man. British Journal of Clinical Pharmacology 18: 581-586, 1984.
     

    1985

  • Eisenhofer G., E.A. Whiteside and R.H. Johnson. Plasma catecholamine responses to change of posture in alcoholics during withdrawal and after continued abstinence from alcohol. Clinical Science 61: 71-78, 1985.
  • Eisenhofer G., D.G. Lambie, E.A. Whiteside and R.H. Johnson. Vasopressin concentrations during alcohol withdrawal. British Journal of Addiction 80: 195-199, 1985.
  • Eisenhofer G.,  D.G. Lambie and R.H. Johnson. ß-adrenoceptor responsiveness and plasma catecholamines as determinants of cardiovascular reactivity to mental stress. Clinical Science 61: 71-78, 1985.
  • Eisenhofer G., D.G. Lambie and R.H. Johnson. No effect of ethanol ingestion on ß-adrenoceptor- mediated circulatory responses to isoprenaline in man. British Journal of Clinical Pharmacology 20: 684-687, 1985.
  • Eisenhofer G., D.G. Lambie and B.J. Robinson. No improvement in ethanol-induced memory deficits after administration of a vasopressin analog. Life Sciences 37: 2499-2505, 1985.
  • Heyward P. and G. Eisenhofer. Ethanol-induced inhibition of the drinking response to hypertonic saline in the rat. Pharmacology, Biochemistry and Behaviour 22: 493-496, 1985.
     

    1986

  • Eisenhofer G. Analytical differences between the determination of plasma catecholamines by liquid chromatography with electrochemical detection and by radioenzymatic assay. Journal of Chromatography 377: 328-331, 1986.
  • Eisenhofer G., D.S. Goldstein, R. Stull, H.R. Keiser, T. Sunderland, D.L. Murphy and I.J. Kopin. Simultaneous liquid-chromatographic determination of 3,4-dihydroxyphenylglycol, catecholamines, and 3,4-dihydroxyphenylalanine in plasma, and their responses to inhibition of monoamine oxidase. Clinical Chemistry 32: 2030-2033, 1986.
  • Eisenhofer G.  Increased voluntary ethanol intake after dietary salt-loading in rats. Pharmacology, Biochemistry and Behaviour 24: 1825-1827, 1986.
  • Eisenhofer G., D.G. Lambie and R.H. Johnson. Effects of ethanol on cardiovascular and catecholamine responses to mental stress. Journal of Psychosomatic Research 30: 93-104,1986.
  • Johnson R.H., G. Eisenhofer and D.G. Lambie. The effects of acute and chronic ingestion of ethanol on the autonomic nervous system. Drug and Alcohol Dependence 18: 319-329,1986.
  • Goldstein D.S., R. Stull, G. Eisenhofer, J.C. Sisson, A. Weder, S.D. Averbuch and H.R. Keiser. Plasma 3,4-Dihydroxyphenylalanine (Dopa) and catecholamines in neuroblastoma or pheochromocytoma. Annals of Internal Medicine 105: 887-888, 1986.
  • Zimlichman R., D.S. Goldstein, G. Eisenhofer, R. Stull and H.R. Keiser. Comparison of noradrenaline and isoprenaline removal in the canine hindlimb and kidney. Clinical and Experimental Pharmacology and Physiology 13: 771-781, 1986.
     

    1987

  • Eisenhofer G., D.G. Lambie and R.H. Johnson.  Effects of ethanol ingestion on blood pressure reactivity. Clinical Science 72: 251-254, 1987.
  • Eisenhofer G., D.S. Goldstein, R.W. Stull, P.W. Gold. H.R. Keiser and I.J. Kopin.  Dissociation between corticotrophin and catecholamine responses to isoprenaline in humans. Clinical and Experimental Pharmacology & Physiology 14: 337-341, 1987.
  • Eisenhofer G.,  T.G. Ropchak,  R.W. Stull,  D.S. Goldstein,  H.R. Keiser and I.J. Kopin.  Dihydroxyphenylglycol and intraneuronal metabolism of endogenous and exogenous norepinephrine in the rat vas deferens. Journal of Pharmacology and Experimental Therapeutics 241: 547-553, 1987.
  • Eisenhofer G., D.S. Goldstein, R. Stull, T.G. Ropchak, H.R. Keiser and I.J. Kopin. Dihydroxyphenylglycol and dihydroxymandelic acid during intravenous infusions of noradrenaline. Clinical Science 73: 123-127,1987.
  • Goldstein D.S., G. Eisenhofer, F.L. Sax, H.R. Keiser and I.J. Kopin. Plasma norepinephrine pharmacokinetics during mental challenge. Psychosomatic Medicine 49: 591-605, 1987.
  • Goldstein D.S., R. Udelsman, G. Eisenhofer, R. Stull, H.R. Keiser and I.J. Kopin. Neuronal source of plasma dihydroxyphenylalanine. Journal of Clinical Endocrinology and Metabolism 64: 856-861, 1987.
     

    1988

  • Eisenhofer G., D.S. Goldstein, T.G. Ropchak and I.J. Kopin. Source and Physiological Significance of Plasma 3,4-Dihydroxyphenylalanine in the Rat. Journal of Neurochemistry 51: 1204-1213, 1988.
  • Eisenhofer G., D.S. Goldstein, T.G. Ropchak, H.Q. Nguyen, H.R. Keiser and I.J. Kopin. Source and physiological significance of plasma 3,4-dihydroxyphenylglycol and 3-methoxy-4-hydroxyphenylglycol. Journal of the Autonomic Nervous System 24: 1-14, 1988.
  • Eisenhofer G., T.G. Ropchak, I.J. Kopin and D.S. Goldstein. Release, metabolism and intraneuronal disposition of exogenous, endogenous and newly synthesized norepinephrine in the rat vas deferens. Journal of Pharmacology and Experimental Therapeutics 245: 81-88, 1988.
  • Eisenhofer G., K.L. Kirk, I.J. Kopin and D.S. Goldstein. Simultaneous determination of endogenous catechols and exogenous 2- and 6- fluorinated catechols in tissue and plasma by using liquid chromatography with electrochemical detection. Journal of Chromatography 431: 156-162, 1988.
  • Goldstein D.S., G. Eisenhofer, R. Stull, C.J. Folio, H.R. Keiser and I.J. Kopin. Plasma dihydroxyphenylglycol and the intraneuronal disposition of norepinephrine in humans. Journal of Clinical Investigation 81: 213-220, 1988.
  • Goldstein D. S. and G. Eisenhofer. Plasma catechols - What do they mean? News in Physiological Sciences 3: 138-144, 1988.
  • Kopin I.J.,  G. Eisenhofer and D.S. Goldstein. Sympathoadrenal medullary system and stress.  Advances in Experimental Medicine and Biology 245: 11-23, 1988.
  • Goldstein D.S., J Brush, G. Eisenhofer, R. Stull and M. Esler. In vivo measurement of neuronal uptake of norepinephrine in the human heart. Circulation 78: 41-48, 1988.
     

    1989

  • Eisenhofer G., D.S. Goldstein and I.J. Kopin. Plasma dihydroxyphenylglycol for estimation of noradrenaline neuronal re-uptake in the sympathetic nervous system in vivo. Clinical Science 76: 171-182, 1989.
  • Eisenhofer G., J.E. Brush, R.O. Cannon, R. Stull, I.J. Kopin and D.S. Goldstein. Plasma dihydroxyphenylalanine and total body and regional noradrenergic activity in humans. Journal of Clinical Endocrinology and Metabolism 68: 247-255, 1989.
  • Eisenhofer G., D. Hovevey-sion, I.J. Kopin, R. Miletich, K.L. Kirk, R. Finn and D.S. Goldstein. Neuronal uptake and metabolism of 2- and 6-fluorodopamine: false neurotransmitters for positron emission tomographic imaging of sympathetically innervated tissues. Journal of Pharmacology and Experimental Therapeutics 248: 419-427, 1989.
  • Brush J.E., G. Eisenhofer, R. Stull, M. Garty, B.J. Maron, R.O. Cannon, J.A. Panza, S.E. Epstein and D.S. Goldstein. Cardiac norepinephrine kinetics in hypertrophic cardiomyopathy. Circulation 79: 836-844, 1989.
  • Goldstein D.S., G. Eisenhofer, M. Garty, F.L. Sax , H.R. Keiser and I.J. Kopin. Pharmacologic and tracer methods to study sympathetic function in primary hypertension. Clinical and Experimental Hypertension A11 (Suppl. 1): 173-189, 1989.
  • Goldstein D.S., G. Eisenhofer, M. Garty, C.J. Folio, R. Stull, J.E. Brush, F.L. Sax, H. R. Keiser and I.J. Kopin. Implications of plasma levels of catechols in the evaluation of sympathoadrenomedullary function. American Journal of Hypertension 2: 133S-139S, 1989.
  • Garty M., A. Deka-Starosta, P.C. Chang, G. Eisenhofer, Z. Zukowska-Grojec, I.J. Kopin and D.S. Goldstein. Plasma levels of catechols during reflexive changes in sympathetic nerve activity. Neurochemical Research 14: 523-531, 1989.
  • Goldstein D.S., R. Stull, G. Eisenhofer and J.R. Gill. Urinary excretion of dihydroxyphenylalanine and dopamine during alterations of dietary salt intake in humans. Clinical Science 76: 517-522, 1989.
     

    1990

  • Eisenhofer G., M. Esler, H.S. Cox, I.T. Meredith, G.L. Jennings, J.E. Brush, and D.S. Goldstein. Differences in the neuronal removal of circulating epinephrine and norepinephrine. Journal of Clinical Endocrinology and Metabolism 70: 1710-1720, 1990.
  • Eisenhofer G., H.S. Cox, and M.D. Esler. Parallel increases in noradrenaline reuptake and release into plasma during activation of the sympathetic nervous system in rabbits. Naunyn Schmiedeberg's Archives of Pharmacology 342: 328-335, 1990.
  • Eisenhofer G., G. Szabo and P.L. Hoffman. Opposite changes in turnover of noradrenaline and dopamine in the CNS of ethanol-dependent mice. Neuropharmacology 29: 37-45, 1990.
  • Esler M., G. Jennings, G. Lambert, I. Meredith, M. Horne and G. Eisenhofer. Overflow of catecholamine neurotransmitters to the circulation: source, fate and functions. Physiological Reviews 70: 963-985, 1990.
  • Medvedev O.S., M. Esler, J.A. Angus, H.S. Cox and G. Eisenhofer. Simultaneous determination of plasma noradrenaline and adrenaline kinetics: Responses to nitroprusside-induced hypotension and 2-deoxyglucose-induced glucopenia in the rabbit. Naunyn Schmiedeberg's Archives of Pharmacology 341: 192-199, 1990.
  • Hovevey-Sion D., G. Eisenhofer, I.J. Kopin, K.L. Kirk, P.C. Chang, K. Szemeredi and D.S. Goldstein. Metabolic fate of injected radiolabelled dopamine and 2-fluorodopamine in rats. Neuropharmacology  29: 881-887, 1990.
  • Goldstein D.S., P.C. Chang, G. Eisenhofer, R. Miletich, R. Finn, J. Bacher, K.L. Kirk, S. Bacharach and I.J. Kopin. Positron emission tomographic imaging of cardiac sympathetic innervation and function. Circulation 81: 1606-1621, 1990.
     

    1991

  • Eisenhofer G., J.J. Smolich, and M.D. Esler. Neuronal reuptake of norepinephrine and production of dihydroxyphenylglycol by cardiac sympathetic nerves in the anesthetized dog. Circulation 84: 1354-1363, 1991.
  • Eisenhofer G., M.D. Esler, D.S. Goldstein, and I.J. Kopin. Neuronal uptake, metabolism, and release of tritium-labeled norepinephrine during assessment of its plasma kinetics. American Journal of Physiology 261: E505-E515, 1991.
  • Eisenhofer G., T. Saigusa, M.D. Esler, H.S. Cox, J.A. Angus and P.K. Dorward. Central sympatho-inhibition and peripheral neuronal uptake blockade after desipramine in rabbits. American Journal of Physiology 260: R824-R832, 1991.
  • Eisenhofer G., M.D. Esler, I.T. Meredith, C. Ferrier, G. Lambert and G. Jennings. Neuronal re-uptake of noradrenaline by sympathetic nerves in humans. Clinical Science 80: 257-263, 1991.
  • Eisenhofer G., H.S. Cox and M.D. Esler. Noradrenaline reuptake and plasma dihydroxyphenylglycol during sustained changes in sympathetic activity in rabbits. Journal of the Autonomic Nervous System 32: 217-232, 1991.
  • Eisenhofer G., I.T. Meredith, C. Ferrier, H.S. Cox, G. Lambert, G.L. Jennings and M.D. Esler. Increased plasma dihydroxyphenylalanine during sympathetic activation in humans is related to increased norepinephrine turnover. Journal of Laboratory and Clinical Medicine 117: 266-273, 1991.
  • Dorward P.K., T. Saigusa and G. Eisenhofer. Differential effects of central and peripheral desipramine on sympathoadrenal function and heart rate in conscious rabbits. Journal of Cardiovascular Pharmacology 17: 519-531, 1991.
  • Goldstein D.S., R.O. Cannon, A. Quyyumi, P. Chang, M. Duncan, J.E. Brush and G. Eisenhofer. Regional extraction of circulating norepinephrine, DOPA, and dihydroxyphenylglycol in humans. Journal of the Autonomic Nervous System 34: 17-36, 1991.
  • Meredith I.T., M.D. Esler, H.S. Cox, G.W. Lambert, G.L. Jennings and G. Eisenhofer. Biochemical evidence of sympathetic denervation of the heart in pure autonomic failure. Clinical Autonomic Research 1: 187-194, 1991.
  • Esler M., G. Eisenhofer, A. Dart, J. Chin, H. Cox,  G. Lambert and G. Jennings. Adrenaline release by the human heart. Clinical and Experimental Pharmacology & Physiology 18: 67-70, 1991.
  • Lambert G.W., G. Eisenhofer, H.S. Cox, M. Horne, V. Kalff, M. Kelly, G.L. Jennings and M.D. Esler. Direct determination of homovanillic acid release from the human brain, an indicator of central dopaminergic activity. Life Sciences 49: 1061-1072, 1991.
  • Esler M., G. Eisenhofer,  J. Chin, G. Jennings, I. Meredith, H. Cox,  G. Lambert, J. Thompson and and A. Dart. Is adrenaline released by sympathetic nerves in man? Clinical Autonomic Research 1: 103-108, 1991.
  • Esler M., G. Wallin, P. Dorward, G. Eisenhofer, R. Westerman, I. Meredith, G. Lambert, H. Cox and G. Jennings. Effects of desipramine on sympathetic nerve firing and norepinephrine spillover to plasma in humans. American Journal of Physiology 260: R817-R823, 1991.
  • Goldstein D.S., P.C. Chang, C. Bruce Smith, P. Herscovitch, S.M. Austin, G. Eisenhofer and I.J. Kopin. Dosimetric estimates for clinical positron emission tomographic scanning after injection of [18F]-6-fluorodopamine. Journal of Nuclear Medicine 32: 102-110, 1991.
  • Goldstein D.S., E. Grossman, M. Tamrat, P.C. Chang,  G. Eisenhofer, J. Bacher, K.L. Kirk, S. Bacharach and I.J. Kopin. Positron emission imaging of cardiac sympathetic innervation and function using 18F-6-fluorodopamine: effects of chemical sympathectomy by 6-hydroxydopamine. Journal of Hypertension 9: 417-423, 1991   
  • Esler M., C. Ferrier, G. Lambert, G. Eisenhofer, H. Cox and G. Jennings. Biochemical evidence of sympathetic hyperactivity in human hypertension. Hypertension 17 (Suppl. 4): III29-35, 1991.
  • Jennings G., M. Esler, A. Dart, A. Dyke, G. Lambert , L. Nelson, H. Cox, E. Dewar, E. Laufer and G. Eisenhofer. Effects of nebivolol on haemodynamics, cardiac dimensions and function, cardiovascular reflexes and biochemical measures of sympathetic activity in normal human subjects. Drug Investigation 3 (Suppl. 1): 51-59, 1991.

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